Itachi Completed 340 Missions, According to the Official Databook

According to the official Naruto databook, Itachi Uchiha completed a total of 340 missions during his time as a shinobi. These include 53 D-rank, 152 C-rank, 134 B-rank, 0 A-rank, and 1 S-rank mission. While the numbers might seem surprising—especially the absence of A-rank missions—they reflect Itachi's unique career path within the Hidden Leaf.

Itachi’s rapid rise through the ranks and eventual induction into the Anbu Black Ops meant that much of his work went beyond the standard mission classification system. His single S-rank mission, though, points to a task of extreme difficulty, likely tied to the heavy decisions and sacrifices he made for the village. These stats highlight both his skill and the unusual trajectory of his life as a ninja.